Name:

Compound Vitamin C & Analgin Injection

Common Capacity:

50ml, 100ml [Concentration will vary, e.g., 250mg/ml Analgin and 50mg/ml Vitamin C]

Applicable Animals:

Global Livestock Application:

• Cattle: Calves, adult cattle (Beef & Dairy)
• Sheep: Lambs, adult sheep
• Goats: Kids, adult goats
• Pigs: Piglets, growing pigs, breeding sows, boars
• Horses: Foals, adult horses (used with caution due to potential side effects in horses compared to other species)
• Camels, Donkeys: (Special farming)

Usage and Dosage:

Administer by Intramuscular (IM) or Intravenous (IV – slow injection only). Dosages are based on species, body weight, and clinical signs.

• Cattle:
  • Adult Cattle: 10 – 25 ml per 100 kg body weight.
  • Calves: 5 – 10 ml per 50 kg body weight.
  • Dosage may be repeated once every 24 hours if necessary, for up to 3-5 days.
• Sheep & Goats:
  • Adult Sheep/Goats: 2 – 5 ml per 50 kg body weight.
  • Lambs/Kids: 0.5 – 1 ml per 10 kg body weight.
  • Dosage may be repeated once every 24 hours if necessary.
• Pigs:
  • Growing Pigs: 5 – 10 ml per 50 kg body weight.
  • Sows/Boars: 10 – 20 ml per head.
  • Dosage may be repeated once every 24 hours if necessary.
• Horses:
  • Adult Horses: 20 – 60 ml per 500 kg body weight (IV route preferred for quicker action and to avoid muscle irritation).
  • Foals: 5 – 15 ml per 100 kg body weight.
  • Note: Use with caution. Intravenous administration should be slow to avoid hypotension.

Consult a veterinarian for specific dosage recommendations and duration of treatment.

Applicable Diseases and Symptoms:

This combination is used for its antipyretic (fever-reducing), analgesic (pain-relieving), and anti-inflammatory effects, complemented by Vitamin C’s immune-boosting properties.

• Fevers of various origins:
  • High fever due to bacterial, viral, or parasitic infections (e.g., pneumonia, enteritis, mastitis, metritis, systemic infections).
  • Post-surgical fever.
• Pain management:
  • Musculoskeletal pain (e.g., laminitis in horses, joint pain, muscle soreness).
  • Colic syndromes in horses (for symptomatic relief of pain).
  • Post-operative pain.
  • Traumatic pain.
• Inflammatory conditions:
  • Acute inflammatory processes where pain and fever are prominent.
• Stress conditions:
  • To aid recovery during periods of stress, such as transport, vaccination, or disease challenge, due to Vitamin C’s role in counteracting stress and enhancing immunity.
• Adjunctive therapy:
  • As an adjunct to specific antimicrobial therapy in cases of infectious diseases to alleviate symptoms and improve animal well-being.

Precautions:

• Route of Administration: Intramuscular injections should be deep, and injection sites rotated to minimize local irritation. Intravenous administration must be slow to prevent side effects like hypotension.
• Drug Interactions: Avoid co-administration with other NSAIDs or nephrotoxic drugs. May interact with anticoagulants.
• Dehydration: Use with caution in severely dehydrated or hypovolemic animals, as NSAIDs can impact renal function.
• Hypersensitivity: Rare cases of anaphylactic reactions can occur, especially with IV administration. Have epinephrine readily available.
• Bleeding Disorders: Analgin can inhibit platelet aggregation; use with caution in animals with existing bleeding disorders.
• Withdrawal Period: Strict adherence to withdrawal periods for meat and milk is crucial to avoid drug residues in human food. Withdrawal periods can vary significantly depending on local regulations and product concentration. Always check the specific product label.
• Storage: Store in a cool, dark place, protected from light. Keep out of reach of children.
• Human Safety: Avoid accidental self-injection. If accidental injection occurs, seek medical attention immediately.

Contraindications:

• Known Hypersensitivity: Do not use in animals hypersensitive to Analgin (metamizole) or Vitamin C.
• Severe Renal or Hepatic Dysfunction: Contraindicated in animals with severe kidney or liver disease.
• Bone Marrow Suppression: Do not use in animals with a history of bone marrow depression or blood dyscrasias, as Analgin can rarely cause agranulocytosis.
• Gastrointestinal Ulceration/Bleeding: Contraindicated in animals with active gastrointestinal ulceration or bleeding.
• Pregnancy/Lactation: Use with caution in pregnant or lactating animals, and only if the benefits outweigh the risks. Analgin may cause prolonged gestation or difficult parturition if used close to term.
• Specific Species: Not recommended for long-term use or in specific situations in horses due to a higher risk of side effects (e.g., gastrointestinal issues, blood dyscrasias).

Post-Treatment Care:

• Monitor Clinical Signs: Continuously monitor the animal’s temperature, pain level, and overall condition.
• Hydration: Ensure adequate hydration, especially in febrile animals.
• Supportive Care: Provide appropriate supportive care, including comfortable bedding, access to fresh water and palatable feed.
• Concurrent Therapy: This product addresses symptoms; identify and treat the underlying cause of fever, pain, or inflammation with appropriate targeted therapy (e.g., antibiotics for bacterial infections).
• Withdrawal Period Compliance: Strictly observe the official withdrawal periods for meat and milk before slaughter or milk collection for human consumption.
• Record Keeping: Maintain accurate records of treatment, dosage, and animal response.